4-(5-Fluoro-2-methoxy-phenyl)-2-hydroxy-4-methyl-2-(trifluoromethyl)pentanal → 1-(2-Acetylaminoquinolin-5-ylamino)-4-(5-fluoro-2-methoxyphenyl)-4-methyl-2-(trifluoromethyl)pentan-2-ol
Reaction equation
[C:22]([CH3:23])(=[O:24])[NH:25][c:26]1[n:27][c:28]2[cH:29][cH:30][cH:31][c:32]([NH2:36])[c:33]2[cH:34][cH:35]1.[F:1][c:2]1[cH:3][cH:4][c:5]([O:20][CH3:21])[c:6]([C:8]([CH2:9][C:10]([CH:11]=[O:12])([C:13]([F:14])([F:15])[F:16])[OH:17])([CH3:18])[CH3:19])[cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([O:20][CH3:21])[c:6]([C:8]([CH2:9][C:10]([CH2:11][NH:36][c:32]2[cH:31][cH:30][cH:29][c:28]3[n:27][c:26]([NH:25][C:22]([CH3:23])=[O:24])[cH:35][cH:34][c:33]32)([C:13]([F:14])([F:15])[F:16])[OH:17])([CH3:18])[CH3:19])[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-dc7ecf88b2bf4f718cb4bb2096ed4e3f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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