Hydrochloride methanol → Hydrochloric Acid

Participants

Reaction Conditions

Reaction Steps

Intermediate 4a (25 mg) obtained in Example 6-1, Step B was added with 10% hydrogen chloride/methanol (10 ml), and the mixture was stirred at 50° C. for 50 hours. The solvent was evaporated under reduced pressure to obtain the title compound as hydrochloride (13 mg).

Provenance & Evidence