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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1962444Generated: October 31, 2026

(S)-3-(tert-Butoxycarbonylamino)-1-(4-bromo-5-isoquinolinesulfonyl)pyrrolidine → Hydrochloric Acid

https://huagongshe.com/reaction/1962444

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-3-(tert-Butoxycarbonylamino)-1-(4-bromo-5-isoquinolinesulfonyl)pyrrolidineHCID 67242852—
ReactantHCID 67243206HCID 67243206—
ProductHydrochloric AcidHCID 313—
ProductHCID 178507922HCID 178507922—

Reaction Steps

Intermediate 16 can be used in the method of Example 6-1, Step A instead of Intermediate 1a, then the resultant can be used in the method of Step B in a similar manner, and then the title compound can be obtained as hydrochloride according to the method described in Example 7-1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08415372B2
Source datasetuspto-grants-2013_04
ORD IDord-24e1c38077b6458b959db5b261cb06db
Source noteuspto-grants-2013_04