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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1962462Generated: October 26, 2026

(S)-3-(tert-butoxycarbonyl)amino-1-(1,4-dichloro-5-isoquinolinesulfonyl)pyrrolidine → Hydrochloric Acid

https://huagongshe.com/reaction/1962462

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-3-(tert-butoxycarbonyl)amino-1-(1,4-dichloro-5-isoquinolinesulfonyl)pyrrolidineHCID 86627808—
Reactant(r/s)-3-(Tert-butoxycarbonyl)amino-1-(1,4-dichloro-5-isoquinolinesulfonyl)pyrrolidineHCID 87322862—
ProductHydrochloric AcidHCID 313—
Product(r/s)-3-Amino-1-(1-amino-4-chloro-5-isoquinolinesulfonyl)pyrrolidineHCID 67242686—

Reaction Steps

Intermediate 26 can be used in the method of Example 39-1 instead of Intermediate 26a to obtain the title compound as hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08415372B2
Source datasetuspto-grants-2013_04
ORD IDord-c3afab37cf9f4c038d967a10cd98bac2
Source noteuspto-grants-2013_04