Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1962465Generated: October 27, 2026

(S)-3-(tert-butoxycarbonyl)amino-1-(1,4-dichloro-5-isoquinolinesulfonyl)pyrrolidine → Hydrochloric Acid

https://huagongshe.com/reaction/1962465

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-3-(tert-butoxycarbonyl)amino-1-(1,4-dichloro-5-isoquinolinesulfonyl)pyrrolidineHCID 86627808—
Reactant(R)-3-(tert-butoxycarbonyl)amino-1-(1,4-dichloro-5-isoquinolinesulfonyl)pyrrolidineHCID 86627809—
ProductHydrochloric AcidHCID 313—
Product(R)-3-Amino-1-(1-amino-4-chloro-5-isoquinolinesulfonyl)pyrrolidineHCID 67246845—

Reaction Steps

Intermediate 26b can be used in the method of Example 39-1 instead of Intermediate 26a to obtain the title compound as hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08415372B2
Source datasetuspto-grants-2013_04
ORD IDord-2511ea8f904e4eb3a6c2af72f3a0e609
Source noteuspto-grants-2013_04