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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1962466Generated: October 26, 2026

(S)-3-(tert-butoxycarbonyl)amino-1-(1,4-dichloro-5-isoquinolinesulfonyl)pyrrolidine → Hydrochloric Acid

https://huagongshe.com/reaction/1962466

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-3-(tert-butoxycarbonyl)amino-1-(1,4-dichloro-5-isoquinolinesulfonyl)pyrrolidineHCID 86627808—
Reactant3-[N-(tert-Butoxycarbonyl)-N-methylamino]-1-(1,4-dichloro-5-isoquinolinesulfonyl)pyrrolidineHCID 86627812—
ProductHydrochloric AcidHCID 313—
Product(r/s)-1-(1-Amino-4-chloro-5-isoquinolinesulfonyl)-3-(methylamino)pyrrolidineHCID 67243276—

Reaction Steps

Intermediate 25 can be used in the method of Example 39-1 instead of Intermediate 26a to obtain the title compound as hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08415372B2
Source datasetuspto-grants-2013_04
ORD IDord-b36897bc157d4c0aa79119ee54b50d09
Source noteuspto-grants-2013_04