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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1962469Generated: October 30, 2026

(S)-3-(tert-Butoxycarbonyl)amino-1-(1-amino-4-chloro-5-isoquinolinesulfonyl)pyrrolidine → Hydrochloric Acid

https://huagongshe.com/reaction/1962469

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-3-(tert-Butoxycarbonyl)amino-1-(1-amino-4-chloro-5-isoquinolinesulfonyl)pyrrolidineHCID 67243408—
Reactant(S)-3-(tert-Butoxycarbonylamino)-1-(1-chloro-4-bromo-5-isoquinolinesulfonyl)pyrrolidineHCID 86627810—
ProductHydrochloric AcidHCID 313—
Product(S)-3-Amino-1-(1-amino-4-bromo-5-isoquinolinesulfonyl)pyrrolidineHCID 67243186—

Reaction Steps

Intermediate 29a was used in the method of Example 39-1, Step B instead of Intermediate 28a to obtain the title compound as hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08415372B2
Source datasetuspto-grants-2013_04
ORD IDord-686cbd7fc5e74ca7bc05076569116b96
Source noteuspto-grants-2013_04