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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1962473Generated: October 31, 2026

(R)-3-[N-(tert-Butoxycarbonyl)-N-methylamino]-1-(1-chloro-4-bromo-5-isoquinolinesulfonyl)pyrrolidine → Hydrochloric Acid

https://huagongshe.com/reaction/1962473

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-3-[N-(tert-Butoxycarbonyl)-N-methylamino]-1-(1-chloro-4-bromo-5-isoquinolinesulfonyl)pyrrolidineHCID 86627806—
Reactant(S)-3-(tert-butoxycarbonyl)amino-1-(1,4-dichloro-5-isoquinolinesulfonyl)pyrrolidineHCID 86627808—
ProductHydrochloric AcidHCID 313—
ProductHCID 67242679HCID 67242679—

Reaction Steps

Intermediate 24b can be used in the method of Example 39-1 instead of Intermediate 26a to obtain the title compound as hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08415372B2
Source datasetuspto-grants-2013_04
ORD IDord-f07d417414e4424eba22f58de4ed202f
Source noteuspto-grants-2013_04