HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 86620768, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 15-Crown-5 | HCID 36336 | — |
| Reactant | Pyridine-3-sulfonyl chloride hydrochloride | HCID 12571517 | — |
| Reactant | HCID 86232752 | HCID 86232752 | — |
| Product | HCID 86620768 | HCID 86620768 | — |
Reaction Steps
By a similar operation as in Reference Example 65 and using 5-(2-fluorophenyl)-4-methyl-1H-pyrrole-3-carbaldehyde (301 mg), sodium hydride (60% in oil, 179 mg), 15-crown-5 (0.88 mL) and pyridin-3-ylsulfonyl chloride hydrochloride (476 mg), the title compound was obtained as white crystals (yield 440 mg, 87%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08415368B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-462e719733f54128b48e952f6b0172e4 |
| Source note | uspto-grants-2013_04 |