HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-1-butanol, (+)- → HCID 49803588, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-1-butanol, (+)- | HCID 120084 | — |
| Reactant | 5-(5-Methyl-3-pyridin-2-yl-isoxazol-4-ylmethoxy)-pyridine-2-carboxylic acid | HCID 66644648 | — |
| Product | HCID 49803588 | HCID 49803588 | 72% |
Reaction Steps
As described for example 7, 5-(5-methyl-3-pyridin-2-yl-isoxazol-4-ylmethoxy)-pyridine-2-carboxylic acid (100 mg, 0.32 mmol) was converted, using S-(+)-2-amino-1-butanol instead of isopropylamine, to the title compound (89 mg, 72%), which was obtained as a white solid. MS: m/e=383.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08415379B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-9b8af8668b6249d1bfba6a6207377217 |
| Source note | uspto-grants-2013_04 |