HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-2-methyl-1-propanol → HCID 49803875, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-2-methyl-1-propanol | HCID 11807 | — |
| Reactant | HCID 66644519 | HCID 66644519 | — |
| Product | HCID 49803875 | HCID 49803875 | 66% |
Reaction Steps
As described for example 23f, 5-[3-(5-fluoro-pyridin-2-yl)-5-methyl-isoxazol-4-ylmethoxy]-pyridine-2-carboxylic acid (75 mg, 0.23 mmol) was converted, using 2-amino-2-methyl-1-propanol instead of isopropylamine, to the title compound (60 mg, 66%), which was obtained as a light-bluish solid. MS: m/e=401.4 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08415379B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-37e31183e44c4edb8e8f830b4adee5c7 |
| Source note | uspto-grants-2013_04 |