Sodium ion → tert-Butyl 2-(4-(7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridin-2-yl)-1H-pyrazol-1-yl)ethyl(2-methoxyethyl)carbamate

HRID 196341Notes

Reaction equation

HRID 196341 reaction equation
[C:50](=[O:51])([O-:52])[O-:53].[CH3:1][O:2][CH2:3][CH2:4][N:5]([C:6]([O:7][C:8]([CH3:9])([CH3:10])[CH3:11])=[O:12])[CH2:13][CH2:14][n:15]1[n:16][cH:17][c:18]([B:20]2[O:21][C:22]([CH3:23])([CH3:24])[C:25]([CH3:26])([CH3:27])[O:28]2)[cH:19]1.[CH3:56][O:57][CH2:58][CH2:59][O:60][CH3:61].[Cl:62][CH2:63][Cl:64].[F:29][c:30]1[c:31]([O:32][c:33]2[c:34]3[c:35]([n:36][cH:37][cH:38]2)[cH:39][c:40]([I:42])[s:41]3)[cH:43][cH:44][c:45]([N+:47](=[O:48])[O-:49])[cH:46]1.[Na+:54].[Na+:55].[cH:65]1[cH:66][cH:67][c:68]([P:69]([Pd:70]([P:71]([c:72]2[cH:73][cH:74][cH:75][cH:76][cH:77]2)([c:78]2[cH:79][cH:80][cH:81][cH:82][cH:83]2)[c:84]2[cH:85][cH:86][cH:87][cH:88][cH:89]2)([P:90]([c:91]2[cH:92][cH:93][cH:94][cH:95][cH:96]2)([c:97]2[cH:98][cH:99][cH:100][cH:101][cH:102]2)[c:103]2[cH:104][cH:105][cH:106][cH:107][cH:108]2)[P:109]([c:110]2[cH:111][cH:112][cH:113][cH:114][cH:115]2)([c:116]2[cH:117][cH:118][cH:119][cH:120][cH:121]2)[c:122]2[cH:123][cH:124][cH:125][cH:126][cH:127]2)([c:128]2[cH:129][cH:130][cH:131][cH:132][cH:133]2)[c:134]2[cH:135][cH:136][cH:137][cH:138][cH:139]2)[cH:140][cH:141]1>>[CH3:1][O:2][CH2:3][CH2:4][N:5]([C:6]([O:7][C:8]([CH3:9])([CH3:10])[CH3:11])=[O:12])[CH2:13][CH2:14][n:15]1[n:16][cH:17][c:18](-[c:40]2[cH:39][c:35]3[c:34]([c:33]([O:32][c:31]4[c:30]([F:29])[cH:46][c:45]([N+:47](=[O:48])[O-:49])[cH:44][cH:43]4)[cH:38][cH:37][n:36]3)[s:41]2)[cH:19]1

Participants

8

Reactant 7

HCID 923Sodium ion2×HCID 6344DichloromethaneHCID 80711,2-DimethoxyethaneHCID 19660Carbonate IonHCID 57919493tert-Butyl 2-methoxyethyl(2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethyl)carbamateHCID 594576617-(2-Fluoro-4-nitrophenoxy)-2-iodothieno[3,2-b]pyridineHCID 178420554HCID 178420554, compound

Product 1

HCID 57919561tert-Butyl 2-(4-(7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridin-2-yl)-1H-pyrazol-1-yl)ethyl(2-methoxyethyl)carbamate

Sources & evidence

ORD record
ord-2d0d5802d9324afd83b3b869390fe66d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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