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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1963682Generated: October 30, 2026

(R)-2-Tosyloxypropionic acid methyl ester → methyl (2S)-2-({3',5-difluoro-4'-[(3-fluorophenyl)sulfonyl]biphenyl-2-yl}oxy)propanoate

https://huagongshe.com/reaction/1963682

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-2-Tosyloxypropionic acid methyl esterHCID 12884153—
Reactant3',5-Difluoro-4'-[(3-fluorophenyl)sulfonyl]biphenyl-2-olHCID 67238560—
Productmethyl (2S)-2-({3',5-difluoro-4'-[(3-fluorophenyl)sulfonyl]biphenyl-2-yl}oxy)propanoateHCID 67239694—

Reaction Steps

The subtitle compound was prepared by the method of example 11 step (vii) using the product of step (iv) and the product of example 11 step (vi).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08415394B2
Source datasetuspto-grants-2013_04
ORD IDord-d7108f858c9a4598aa06c16881e32dd6
Source noteuspto-grants-2013_04