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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1963689Generated: October 27, 2026

5-Fluoro-2-methoxyphenylboronic acid → 2-Chlorophenyl 3,5'-difluoro-2'-methoxybiphenyl-4-yl sulfone

https://huagongshe.com/reaction/1963689

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Fluoro-2-methoxyphenylboronic acidHCID 2782673—
Reactant4-Bromo-1-[(2-chlorophenyl)sulfonyl]-2-fluorobenzeneHCID 67240314—
Product2-Chlorophenyl 3,5'-difluoro-2'-methoxybiphenyl-4-yl sulfoneHCID 67242320—

Reaction Steps

The subtitle compound was prepared by the method of example 2 step (ii) using the product of step (ii) and 5-fluoro-2-methoxybenzene boronic acid which was used directly in step (iv) without further characterisation.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08415394B2
Source datasetuspto-grants-2013_04
ORD IDord-8dba551bbee04b5fb2fe902139ea3bc5
Source noteuspto-grants-2013_04