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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1963693Generated: October 31, 2026

(R)-2-Tosyloxypropionic acid methyl ester → methyl (2S)-2-{[3'-chloro-5-fluoro-4'-(phenylsulfonyl)biphenyl-2-yl]oxy}propanoate

https://huagongshe.com/reaction/1963693

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-2-Tosyloxypropionic acid methyl esterHCID 12884153—
Reactant3'-Chloro-5-fluoro-4'-(phenylsulfonyl)biphenyl-2-olHCID 67240365—
Productmethyl (2S)-2-{[3'-chloro-5-fluoro-4'-(phenylsulfonyl)biphenyl-2-yl]oxy}propanoateHCID 67239082—

Reaction Steps

The subtitle compound was prepared by the method of example 11 step (vii) using the product of step (iii) and the product of example 11 step (vi).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08415394B2
Source datasetuspto-grants-2013_04
ORD IDord-d3f6df985fd145faa8c6094cd9013df1
Source noteuspto-grants-2013_04