HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 2-(3-Isopropylphenylamino)benzo[d]thiazol-5-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | N-(3-isopropylphenyl)-5-methoxybenzo[d]thiazol-2-amine | HCID 86045335 | — |
| Product | 2-(3-Isopropylphenylamino)benzo[d]thiazol-5-ol | HCID 86045337 | — |
Reaction Steps
N-(3-isopropylphenyl)-5-methoxybenzo[d]thiazol-2-amine was charged with hydrobromic acid (45%) and subjected to microwave at 170° C. for 10 minutes. Reaction was then neutralized with sodium carbonate (saturated solution) and partitioned between ethyl acetate and water. The organic layer was separated, washed with brine, dried over sodium sulfate and concentrated to give 2-(3-isopropylphenylamino)benzo[d]thiazol-5-ol. HPLC=4.63 min; MS: MH+=285.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08415382B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-183fe40092564db1a7259aadfb18e865 |
| Source note | uspto-grants-2013_04 |