HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-tert-Butyl-1-fluoro-2-nitrobenzene → 5-Tert-butyl-2-fluoroaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-tert-Butyl-1-fluoro-2-nitrobenzene | HCID 22741893 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5-Tert-butyl-2-fluoroaniline | HCID 20706566 | — |
Reaction Steps
To 4-tert-butyl-1-fluoro-2-nitrobenzene in methanol was added a catalytic amount of palladium on carbon (10%). The mixture was allowed to stir for 1 h at room temperature under an atmosphere of hydrogen. Mixture was filtered though celite and concentrated to afford 5-tert-butyl-2-fluorobenzenamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08415382B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-86d34495a3394726a043361a963fb34b |
| Source note | uspto-grants-2013_04 |