HCID 59610198, compound → HCID 131730508, compound
Reaction equation
CC1(C)C(C)(C)OB([C:9]2[CH:14]=[CH:13][C:12]([C:15]3[N:16]=[C:17]([C@@H:20]4[CH2:24][CH2:23][CH2:22][N:21]4[C:25]([O:27][C:28]([CH3:31])([CH3:30])[CH3:29])=[O:26])[S:18][CH:19]=3)=[CH:11][CH:10]=2)O1.Br[C:34]1[CH:39]=[CH:38][C:37]([C:40]2[S:44][C:43]([C@@H:45]3[CH2:49][CH2:48][CH2:47][N:46]3[C:50]([O:52][C:53]([CH3:56])([CH3:55])[CH3:54])=[O:51])=[N:42][CH:41]=2)=[CH:36][CH:35]=1.CC1(C)C(C)(C)OB(C2C=CC(C3SC([C@@H]4CCCN4C(OC(C)(C)C)=O)=NC=3)=CC=2)O1>>[C:28]([O:27][C:25]([N:21]1[CH2:22][CH2:23][CH2:24][C@H:20]1[C:17]1[S:18][CH:19]=[C:15]([C:12]2[CH:13]=[CH:14][C:9]([C:34]3[CH:39]=[CH:38][C:37]([C:40]4[S:44][C:43]([C@@H:45]5[CH2:49][CH2:48][CH2:47][N:46]5[C:50]([O:52][C:53]([CH3:55])([CH3:54])[CH3:56])=[O:51])=[N:42][CH:41]=4)=[CH:36][CH:35]=3)=[CH:10][CH:11]=2)[N:16]=1)=[O:26])([CH3:31])([CH3:29])[CH3:30]Participants
4
Procedure
Compound 43a was prepared in the same manner as described in Example 4 except that Compounds 13a and 21a, instead of Compounds 2a and 3a, were used.
Sources & evidence
- ORD record
- ord-a2c503fa99584021b87fe1250486f67d
- Source dataset
- uspto-grants-2013_04
- Patent number
- US08415482B2
Reaction notes
Loading…