反应详情

Using the same method as in Example 1-(ii), 4′-fluorobiphenyl-4-yl amine was reacted with the (2-([4-chloro-2-(methoxycarbonyl)phenyl]amino)-2-oxoethoxy)acetic acid obtained in Example 1-(i) to give 5-chloro-2-[((2-[(4′-fluorobiphenyl-4-yl)amino]-2-oxoethoxy)acetyl)amino]benzoic acid.methyl ester (yield: 86%).