HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-([4-Chloro-2-(methoxycarbonyl)phenyl]amino)-5-oxopentanoic acid → 5-Chloro-2-[(5-([5-(furan-3-yl)-2-methylphenyl]amino)-5-oxopentanoyl)amino]benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-([4-Chloro-2-(methoxycarbonyl)phenyl]amino)-5-oxopentanoic acid | HCID 51040152 | — |
| Reactant | 5-(Furan-3-yl)-2-methylaniline | HCID 63949753 | — |
| Product | 5-Chloro-2-[(5-([5-(furan-3-yl)-2-methylphenyl]amino)-5-oxopentanoyl)amino]benzoic acid | HCID 44251225 | — |
Reaction Steps
Using the same method as in Example 15-(i), 5-(furan-3-yl)-2-methylaniline was reacted with the 5-([4-chloro-2-(methoxycarbonyl)phenyl]amino)-5oxopentanoic acid obtained in Example 31-(i) to give 5-chloro-2-[(5-([5-(furan-3-yl)-2-methylphenyl]amino)-5-oxopentanoyl)amino]benzoic acid.methyl ester (yield: 73%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08415479B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-d1e72c5450af4290b39d0cb5957a8140 |
| Source note | uspto-grants-2013_04 |