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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1964024Generated: October 31, 2026

3-(3-Furanyl)benzenamine → 5-Chloro-2-(([(2-([3-(furan-3-yl)phenyl]amino)-2-oxoethyl)sulfanyl]acetyl)amino)benzoic acid

https://huagongshe.com/reaction/1964024

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(3-Furanyl)benzenamineHCID 16203332—
Reactant[(2-([4-Chloro-2-(methoxycarbonyl)phenyl]amino)-2-oxoethyl)sulfanyl]acetic acidHCID 51040153—
Product5-Chloro-2-(([(2-([3-(furan-3-yl)phenyl]amino)-2-oxoethyl)sulfanyl]acetyl)amino)benzoic acidHCID 44250694—

Reaction Steps

Using the same method as in Example 15-(ii), 3-(furan-3-yl)aniline was reacted with the [(2-([4-chloro-2-(methoxycarbonyl)phenyl]amino)-2-oxoethyl)sulfanyl]acetic acid obtained in Example 12-(i) to give 5-chloro-2-(([(2-([3-(furan-3-yl)phenyl]amino)-2-oxoethyl)sulfanyl]acetyl)amino)benzoic acid.methyl ester (yield: 65%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08415479B2
Source datasetuspto-grants-2013_04
ORD IDord-8eaf8960fb7b4e2282d8d2f97c28a9de
Source noteuspto-grants-2013_04