Furan-3-boronic acid → HCID 66878166, compound

HRID 1964028Notes

Reaction equation

HRID 1964028 reaction equation
[O:1]1[CH:5]=[CH:4][C:3](B(O)O)=[CH:2]1.Br[C:10]1[CH:11]=[C:12]([CH:14]=[CH:15][C:16]=1[F:17])[NH2:13]>>[F:17][C:16]1[CH:15]=[CH:14][C:12]([NH2:13])=[CH:11][C:10]=1[C:3]1[CH:4]=[CH:5][O:1][CH:2]=1

Participants

3

Reactant 2

HCID 2734358Furan-3-boronic acidHCID 27792863-Bromo-4-fluoroaniline

Product 1

HCID 66878166HCID 66878166, compoundYield 65%

Procedure

Using the same method as in Example 19-(ii), 3-furanboronic acid was reacted with the 3-bromo 4-fluoro-aniline to give 4-fluoro-3-(furan-3-yl)aniline (yield: 65%).

Sources & evidence

ORD record
ord-de543ac146c2445ba3e40b2ba4134c5e
Source dataset
uspto-grants-2013_04
Patent number
US08415479B2

Reaction notes

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