HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzo[b]furan-2-boronic acid → 2-([(2-([3-(1-Benzofuran-2-yl)phenyl]amino)-2-oxoethoxy)acetyl]amino)-5-chlorobenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzo[b]furan-2-boronic acid | HCID 2776266 | — |
| Reactant | 2-[((2-[(3-Bromophenyl)amino]-2-oxoethoxy)acetyl)amino]-5-chlorobenzoic acid | HCID 86653349 | — |
| Product | 2-([(2-([3-(1-Benzofuran-2-yl)phenyl]amino)-2-oxoethoxy)acetyl]amino)-5-chlorobenzoic acid | HCID 44250424 | — |
Reaction Steps
Using the same method as in Example 19-(ii), 2-benzofuran boronic acid was reacted with the 2-[((2-[(3-bromophenyl)amino]-2-oxoethoxy)acetyl)amino]-5-chlorobenzoic acid.methyl ester obtained in Example 19-(i) to give 2-([(2-([3-(1-benzofuran-2-yl)phenyl]amino)-2-oxoethoxy)acetyl]amino)-5-chlorobenzoic acid.methyl ester (yield: 44%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08415479B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-2e2f69dc154441a59623070b8560db92 |
| Source note | uspto-grants-2013_04 |