2-Amino-5-chlorobenzoic acid → HCID 44250423, compound

HRID 1964032Notes

Reaction equation

HRID 1964032 reaction equation
[NH2:1][C:2]1[CH:10]=[CH:9][C:8]([Cl:11])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[O:12]1[CH:16]=[CH:15][C:14]([C:17]2[CH:18]=[C:19]([NH:23][C:24](=[O:29])[CH2:25][C:26](O)=[O:27])[CH:20]=[CH:21][CH:22]=2)=[CH:13]1>>[Cl:11][C:8]1[CH:9]=[CH:10][C:2]([NH:1][C:26](=[O:27])[CH2:25][C:24]([NH:23][C:19]2[CH:20]=[CH:21][CH:22]=[C:17]([C:14]3[CH:15]=[CH:16][O:12][CH:13]=3)[CH:18]=2)=[O:29])=[C:3]([CH:7]=1)[C:4]([OH:6])=[O:5]

Participants

3

Reactant 2

HCID 124762-Amino-5-chlorobenzoic acidHCID 66876770HCID 66876770, compound

Product 1

HCID 44250423HCID 44250423, compound

Procedure

Using the same method as in Example 15-(i), 2-amino-5-chlorobenzoic acid.benzylester was reacted with the 3-([3-(furan-3-yl)phenyl]amino)-3-oxopropanoic acid to give 5-chloro-2-[(3-([3-(furan-3-yl)phenyl]amino)-3-oxopropanoyl)amino]benzoic acid.benzylester (yield: 48%).

Sources & evidence

ORD record
ord-eec1c9b6f7fe4fadbf2becd7ded93d27
Source dataset
uspto-grants-2013_04
Patent number
US08415479B2

Reaction notes

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