Benzenemethanamine, 3-bromo- → HCID 63949953, compound

HRID 1964033Notes

Reaction equation

HRID 1964033 reaction equation
[O:1]1[CH:5]=[CH:4][C:3](B(O)O)=[CH:2]1.Br[C:10]1[CH:11]=[C:12]([CH:15]=[CH:16][CH:17]=1)[CH2:13][NH2:14]>>[O:1]1[CH:5]=[CH:4][C:3]([C:10]2[CH:11]=[C:12]([CH2:13][NH2:14])[CH:15]=[CH:16][CH:17]=2)=[CH:2]1

Participants

3

Reactant 2

HCID 457587Benzenemethanamine, 3-bromo-HCID 2734358Furan-3-boronic acid

Product 1

HCID 63949953HCID 63949953, compoundYield 76%

Procedure

Using the same method as in Example 19-(ii), 3-furanboronic acid was reacted with the 3-bromobenzyl amine to give 1-[3-(furan-3-yl)phenyl]methanamine (yield: 76%).

Sources & evidence

ORD record
ord-ce70d99767d14f57b68b911b8b2a3903
Source dataset
uspto-grants-2013_04
Patent number
US08415479B2

Reaction notes

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