Benzenamine, 2-phenoxy- → HCID 44250693, compound

HRID 1964040Notes

Reaction equation

HRID 1964040 reaction equation
[O:1]([C:8]1[CH:14]=[CH:13][CH:12]=[CH:11][C:9]=1[NH2:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([NH:22][C:23](=[O:30])[CH2:24][S:25][CH2:26][C:27](O)=[O:28])=[C:18]([C:31]([O:33]C)=[O:32])[CH:17]=1>>[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([NH:22][C:23](=[O:30])[CH2:24][S:25][CH2:26][C:27](=[O:28])[NH:10][C:9]2[CH:11]=[CH:12][CH:13]=[CH:14][C:8]=2[O:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)=[C:18]([CH:17]=1)[C:31]([OH:33])=[O:32]

Participants

3

Reactant 2

HCID 75899Benzenamine, 2-phenoxy-HCID 51040153[(2-([4-Chloro-2-(methoxycarbonyl)phenyl]amino)-2-oxoethyl)sulfanyl]acetic acid

Product 1

HCID 44250693HCID 44250693, compound

Procedure

Using the same method as in Example 1-(ii), 2-phenoxyaniline was reacted with the [(2-([4-chloro-2-(methoxycarbonyl)phenyl]amino)-2-oxoethyl)sulfanyl]acetic acid obtained in Example 12-(i) to give 5-chloro-2-([((2-oxo-2-[(2-phenoxyphenyl)amino]ethyl)sulfanyl)acetyl]amino)benzoic acid.methyl ester (yield: 72%).

Sources & evidence

ORD record
ord-d46a44e5b7c64fdea1715d9d77ae3d61
Source dataset
uspto-grants-2013_04
Patent number
US08415479B2

Reaction notes

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