4-(3-Furanyl)benzenamine → HCID 44250491, compound

HRID 1964049Notes

Reaction equation

HRID 1964049 reaction equation
[O:1]1[CH:5]=[CH:4][C:3]([C:6]2[CH:12]=[CH:11][C:9]([NH2:10])=[CH:8][CH:7]=2)=[CH:2]1.[Cl:13][C:14]1[CH:19]=[CH:18][C:17]([NH:20][C:21](=[O:28])[CH2:22][O:23][CH2:24][C:25](O)=[O:26])=[C:16]([C:29]([O:31]C)=[O:30])[CH:15]=1>>[Cl:13][C:14]1[CH:19]=[CH:18][C:17]([NH:20][C:21](=[O:28])[CH2:22][O:23][CH2:24][C:25]([NH:10][C:9]2[CH:11]=[CH:12][C:6]([C:3]3[CH:4]=[CH:5][O:1][CH:2]=3)=[CH:7][CH:8]=2)=[O:26])=[C:16]([CH:15]=1)[C:29]([OH:31])=[O:30]

Participants

3

Reactant 2

HCID 444209884-(3-Furanyl)benzenamineHCID 510399542-(2-((4-Chloro-2-(methoxycarbonyl)phenyl)amino)-2-oxoethoxy)acetic acid

Product 1

HCID 44250491HCID 44250491, compound

Procedure

Using the same method as in Example 1-(ii), 4-(furan-3-yl)aniline was reacted with the (2-([4-chloro-2-(methoxycarbonyl)phenyl]amino)-2-oxoethoxy)acetic acid obtained in Example 1-(i) to give 5-chloro-2-([(2-([4-(furan-3-yl)phenyl]amino)-2-oxoethoxy)acetyl]amino)benzoic acid.methyl ester (yield: 84%).

Sources & evidence

ORD record
ord-e07807d0ce0940548903f79e741b7440
Source dataset
uspto-grants-2013_04
Patent number
US08415479B2

Reaction notes

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