Benzene, 1-bromo-3-nitro- → HCID 86653354, compound

HRID 1964057Notes

Reaction equation

HRID 1964057 reaction equation
CC1(C)C(C)(C)OB([C:9]2[CH:10]=[N:11][N:12]([C:14]([OH:16])=[O:15])[CH:13]=2)O1.Br[C:19]1[CH:24]=[CH:23][CH:22]=[C:21]([N+:25]([O-:27])=[O:26])[CH:20]=1>>[N+:25]([C:21]1[CH:20]=[C:19]([C:9]2[CH:10]=[N:11][N:12]([C:14]([OH:16])=[O:15])[CH:13]=2)[CH:24]=[CH:23][CH:22]=1)([O-:27])=[O:26]

Participants

3

Reactant 2

HCID 11457Benzene, 1-bromo-3-nitro-HCID 21981000HCID 21981000, compound

Product 1

HCID 86653354HCID 86653354, compound

Procedure

Using the same method as in Example 5-(i), 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylic acid.tert-butyl was reacted with 1-bromo-3-nitrobenzene to give 4-(3-nitrophenyl)-1H-pyrazole-1-carboxylic acid.tert-butyl (yield: 64%).

Sources & evidence

ORD record
ord-50ba3b121afb43bba62633d6eaae4716
Source dataset
uspto-grants-2013_04
Patent number
US08415479B2

Reaction notes

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