HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(3-nitrophenyl)-1H-pyrazole → 3-(1H-pyrazol-4-yl)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(3-nitrophenyl)-1H-pyrazole | HCID 66876910 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 3-(1H-pyrazol-4-yl)aniline | HCID 63338282 | 99.6% |
Reaction Steps
A 5 mL ethyl acetate solution of 300 mg (1.59 mmol) of 4-(3-nitrophenyl)-1H-pyrazole was added to 30 mg of 5% Pd—C, and stirred under a hydrogen atmosphere at room temperature overnight. The reaction solution was filtered through celite, and the filtrate was condensed and dried to give 252 mg of 3-(1H-pyrazol-4-yl)aniline (yield: 99%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08415479B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-16db744df37c4bc68bed8563600a5825 |
| Source note | uspto-grants-2013_04 |