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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 196427Generated: October 30, 2026

Toluene → Ethyl 2-ethynyl-4-methylthiazole-5-carboxylate

https://huagongshe.com/reaction/196427

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantTrimethylsilylacetyleneHCID 66111—
ReactantDiisopropylethylamineHCID 81531—
ReactantEthyl 2-bromo-4-methyl-1,3-thiazole-5-carboxylateHCID 2824057—
ProductEthyl 2-ethynyl-4-methylthiazole-5-carboxylateHCID 59179676—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-5159c62eee214c31be982020eb645419
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)