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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1964488Generated: October 29, 2026

2-(tert-Butyl)-5-nitro-1H-indole → (R)-N-(2-tert-butyl-1-(2,3-dihydroxypropyl)-1H-indol-5-yl)-1-(3,4-dihydroxyphenyl)cyclopropanecarboxamide

https://huagongshe.com/reaction/1964488

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(tert-Butyl)-5-nitro-1H-indoleHCID 10584913—
Reactant1-(3,4-Dihydroxyphenyl)cyclopropanecarboxylic acidHCID 59129368—
Product(R)-N-(2-tert-butyl-1-(2,3-dihydroxypropyl)-1H-indol-5-yl)-1-(3,4-dihydroxyphenyl)cyclopropanecarboxamideHCID 59129352—

Reaction Steps

(R)—N-(2-tert-butyl-1-(2,3-dihydroxypropyl)-1H-indol-5-yl)-1-(3,4-dihydroxyphenyl)cyclopropanecarboxamide was prepared using an experimental procedure similar to Example 72 from 1-(3,4-dihydroxyphenyl)cyclopropanecarboxylic acid and 2-tert-butyl-5-nitro-1H-indole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08415387B2
Source datasetuspto-grants-2013_04
ORD IDord-438d5ab7afc646f2a18016f0b99ec33b
Source noteuspto-grants-2013_04