Epichlorohydrin → HCID 66723969, compound

Participants

Reaction Conditions

Reaction Steps

To a four-necked flask equipped with a thermometer, a cooling tube, and a stirrer were charged with 610.6 g (6.6 mol) of epichlorohydrin and 509.3 g of 2-propanol, and then the inside of the four-necked flask was purged with nitrogen. The temperature was raised to 60° C. and 203.7 g (1.1 mol) of a powder of 4-phenoxyaniline was added over three hours. Moreover, the temperature was raised to 80° C. and the reaction was continued at 80° C. for 18 hours under stirring to produce 4-phenoxy-N,N-bis(2-hydroxy-3-chloropropyl)aniline.

Provenance & Evidence