Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(S)-1-Phenyl-3-propanolamine → (2S)-N-[(1S)-3-hydroxy-1-phenylpropyl]-3-[(4-tert-pentylphenyl)sulfonyl]-1,3-thiazolidine-2-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (S)-1-Phenyl-3-propanolamine | HCID 2734520 | — |
| 반응물 | HCID 68623277 | HCID 68623277 | — |
| 생성물 | (2S)-N-[(1S)-3-hydroxy-1-phenylpropyl]-3-[(4-tert-pentylphenyl)sulfonyl]-1,3-thiazolidine-2-carboxamide | HCID 57462299 | — |
반응 단계
Following the general strategies and protocols outlined in Example 1, starting from 3-[(4-tert-pentylphenyl)sulfonyl]-1,3-thiazolidine-2-carboxylic acid (Intermediate 8) and commercial (3S)-3-amino-3-phenyl-1-propanol, the title compound was obtained in 99% purity by HPLC.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08415480B2 |
| 출처 데이터셋 | uspto-grants-2013_04 |
| ORD ID | ord-bb98d9dfce334673abd918c39224dd97 |
| 출처 메모 | uspto-grants-2013_04 |