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2,3,6-Trifluorobenzaldehyde → [5-(3-Methanesulfonyl-phenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-(2,3,6-trifluoro-phenyl)-methanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,3,6-Trifluorobenzaldehyde | HCID 517845 | — |
| 反応物 | 5-(Pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine | HCID 51358551 | — |
| 反応物 | 5-(3-methanesulfonyl-phenyl)-1H-pyrrolo[2,3-b]pyridine | HCID 58086899 | — |
| 生成物 | [5-(3-Methanesulfonyl-phenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-(2,3,6-trifluoro-phenyl)-methanone | HCID 58086752 | — |
反応手順
was prepared using the protocol of Steps 3 and 4 of Scheme 17, substituting propane-2-sulfonic acid (2,4-difluoro-3-formyl-phenyl)-amide with 2,3,6-Trifluoro-benzaldehyde and 5-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridine 89 with 5-(3-methanesulfonyl-phenyl)-1H-pyrrolo[2,3-b]pyridine in Step 3. MS(ESI) [M−H+]−=429.0.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08415469B2 |
| 出典データセット | uspto-grants-2013_04 |
| ORD ID | ord-ed1afcea4b3d4e20993cadba3364f60b |
| 出典メモ | uspto-grants-2013_04 |