HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(Tert-butyl)pyridin-3-amine → (6-Benzyl-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidin-4-yl)-(6-tert-butyl-pyridin-3-yl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(Tert-butyl)pyridin-3-amine | HCID 25026386 | — |
| Reactant | 6-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido(4,3-d)pyrimidine | HCID 25324046 | — |
| Product | (6-Benzyl-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidin-4-yl)-(6-tert-butyl-pyridin-3-yl)-amine | HCID 59346474 | — |
Reaction Steps
The title compound was prepared substantially according to the procedure given for Compound 1A, using 6-benzyl-4-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine (Intermediate 2), and 6-tert-butyl-pyridin-3-ylamine to give the desired N-benzyl intermediate as a brown solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07745451B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-398a72afc5a34156bcc484a090bd0256 |
| Source note | uspto-grants-2010_06 |