HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59803850, compound → HCID 59803901, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59803850 | HCID 59803850 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 59803901 | HCID 59803901 | — |
Reaction Steps
To 3-(4-Benzyloxy-2,5-difluoro-benzyl)-1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine (602, 0.70 g, 0.0014 mol) in methanol (30.0 mL) was added 50%© palladium hydroxide on carbon (0.1 g) under an atmosphere of hydrogen. The reaction was stirred at room temperature overnight. The reaction was filtered and concentrated to give a colorless oil (603, 0.47 g. 82.0%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08415469B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-702e209f88cd49a3b4792399ac93199f |
| Source note | uspto-grants-2013_04 |