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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 19650Generated: October 26, 2026

2,3-Dichloropyridine → (6-tert-Butyl-pyridin-3-yl)-[6-(3-chloro-pyridin-2-yl)-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidin-4-yl]-amine

https://huagongshe.com/reaction/19650

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-DichloropyridineHCID 16988—
Reactant(5,6,7,8-Tetrahydro-pyrido[4,3-d]pyrimidin-4-yl)-(6-tert-butyl-pyridin-3-yl)-amineHCID 59346577—
Product(6-tert-Butyl-pyridin-3-yl)-[6-(3-chloro-pyridin-2-yl)-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidin-4-yl]-amineHCID 59346546—

Reaction Steps

The title compound was prepared according to the procedure given for Compound 1C by reacting (5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidin-4-yl)-(6-tert-butyl-pyridin-3-yl)-amine with 2,3-dichloropyridine to give the desired compound as an off-white powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07745451B2
Source datasetuspto-grants-2010_06
ORD IDord-08369462b61f4121b5919fa794c65df0
Source noteuspto-grants-2010_06