反应详情

A mixture containing 55 (7.2 g, 15.6 mmol) and 10% Pd-on-carbon (wet, 1.7 g, 1.5 mmol) in MeOH (200 mL) were stirred vigorously under an atmosphere of H2. After 2 h, the was removed by filtration and the filtrate was diluted with toluene and concentrated in vacuo to afford 6.1 g of 56 as an off-white-colored foam which was used without further purification. Mass spectrum, m/z [326.7] (M+H)+.

1. customthe was removed by filtration
2. additionthe filtrate was diluted with toluene
3. concentrationconcentrated in vacuo