HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromodiphenylmethane → 1-(diphenylmethyl)-7-fluoro-1H-indole-2,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromodiphenylmethane | HCID 236603 | — |
| Reactant | 7-Fluoroisatin | HCID 586418 | — |
| Reactant | 2,3-dihydro-6H-[1,4]dioxino[2,3-f]indole-7,8-dione | HCID 2029802 | — |
| Reactant | 2-(Bromomethyl)-5-(trifluoromethyl)furan | HCID 2794605 | — |
| Product | 1-(diphenylmethyl)-7-fluoro-1H-indole-2,3-dione | HCID 67356678 | — |
Reaction Steps
Following the procedure as described in PREPARATION 26A and making non-critical variations using 7-fluoroisatin to replace 2,3-dihydro-6H-[1,4]dioxino[2,3-f]indole-7,8-dione, and bromodiphenylmethane to replace 2-(bromomethyl)-5-(trifluoromethyl)furan, 7-fluoro-1-(diphenylmethyl)-1H-indole-2,3-dione was obtained (80%): MS (ES+) m/z 353.7 (M+23).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08415370B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-f6738e48b99842acae35ff603a2db109 |
| Source note | uspto-grants-2013_04 |