6-Bromo-2-chlorobenzothiazole → 6-Bromo-2-mercaptobenzothiazole

Participants

Reaction Conditions

Reaction Steps

A mixture of 6-bromo-2-chlorobenzo[d]thiazole (250 mg, 1 mmol) and thiourea (228 mg, 3 mmol) in 2 mL of MeOH in a microwave tube was heated in a microwave reactor for 10 min at 120° C. The mixture was concentrated and the solid was collected through filtration and washed with water and dried under high vacuum to afford 6-bromobenzo[d]thiazole-2-thiol as a yellow solid (200 mg, 81%). MS (ESI) m/z 247.9 (M+H+).

Provenance & Evidence