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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 196606Generated: October 26, 2026

Tetrahydrofuran → Tert-butyl 4-(4-chloro-3-methoxyphenyl)-4-hydroxy-3,3-dimethylpiperidine-1-carboxylate

https://huagongshe.com/reaction/196606

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant5-Bromo-2-chloroanisoleHCID 2769567—
Reactanttert-Butyl 3,3-dimethyl-4-oxopiperidine-1-carboxylateHCID 22278899—
ReactantButyllithiumHCID 178418339—
ProductTert-butyl 4-(4-chloro-3-methoxyphenyl)-4-hydroxy-3,3-dimethylpiperidine-1-carboxylateHCID 57889543—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-31fc804b5f924f9ea3ea56d4c9347f6b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)