HCID 58026771, compound → HCID 58026933, compound

HRID 1966269Notes

Reaction equation

HRID 1966269 reaction equation
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]2[C:16]3[C:11](=[N:12][CH:13]=[CH:14][CH:15]=3)[O:10][C:9](=[O:17])[C:8]=2[CH:18]=1)([O-])=O>CO.[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]2[C:16]3[C:11](=[N:12][CH:13]=[CH:14][CH:15]=3)[O:10][C:9](=[O:17])[C:8]=2[CH:18]=1

Participants

4

Reactant 1

HCID 58026771HCID 58026771, compound

Product 1

HCID 58026933HCID 58026933, compoundYield 92%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

8-Nitro-4-azabenzo[c]chromen-6-one (Reference Compound No. 1-3-(4), 368 mg, 1.52 mmol) was dissolved in methanol (10 mL), then 5% palladium on charcoal (37 mg) was added thereto, and then the reaction mixture was stirred under hydrogen atmosphere at room temperature for 4 days. After the mixture was filtered, the solvent was removed under reduced pressure. Chloroform was added to the obtained residue, and then filtered to give the titled reference compound (298 mg) as a yellow solid. (Yield 92%)

Workup

  1. filtrationAfter the mixture was filtered
  2. customthe solvent was removed under reduced pressure
  3. additionChloroform was added to the obtained residue
  4. filtrationfiltered

Sources & evidence

ORD record
ord-d24cde5e0a8e45558eaa3dde2eda56c5
Source dataset
uspto-grants-2013_04
Patent number
US08420635B2

Reaction notes

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