HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetaldehyde → HCID 57820549, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetaldehyde | HCID 177 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | HCID 57820277 | HCID 57820277 | — |
| Solvent | Sodium cyanoborohydride | HCID 5003444 | — |
| Product | HCID 57820549 | HCID 57820549 | — |
Reaction Steps
The compound is obtained by treating [7-(3,5-difluoro-4-morpholin-4-ylmethyl-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]-((S)-3-morpholin-3-yl-phenyl)-amine (Example 507) with acetaldehyde in methanol and sodium cyanoborohydride at rt to 60° C. HPLC: tR=0.63 min (Method G); MS-ES: (M+H)+=535
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08420657B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-99186a628b7348328c00b327b44d7d94 |
| Source note | uspto-grants-2013_04 |