HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → HCID 57820456, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | HCID 57820277 | HCID 57820277 | — |
| Solvent | Sodium cyanoborohydride | HCID 5003444 | — |
| Product | HCID 57820456 | HCID 57820456 | — |
Reaction Steps
The compound is obtained by treating [7-(3,5-difluoro-4-morpholin-4-ylmethyl-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]-((S)-3-morpholin-3-yl-phenyl)-amine (Example 507) with formaldehyde in methanol and sodium cyanoborohydride at rt to 60° C. HPLC: tR=0.61 min (Method G); MS-ES: (M+H)+=521
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08420657B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-b3ccf08b0b25462fbd46d345ed4b1ecb |
| Source note | uspto-grants-2013_04 |