HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Phenylmethoxy)acetaldehyde → HCID 57820234, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Phenylmethoxy)acetaldehyde | HCID 108989 | — |
| Reactant | HCID 57820172 | HCID 57820172 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Sodium cyanoborohydride | HCID 5003444 | — |
| Product | HCID 57820234 | HCID 57820234 | — |
Reaction Steps
The compound is obtained by treating [7-(3,5-difluoro-4-morpholin-4-ylmethyl-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]-((S)-4-morpholin-3-yl-phenyl)-amine (Example 511) with benzyloxyacetaldehyde in methanol and sodium cyanoborohydride at 60° C. HPLC: tR=0.78 min (Method G); MS-ES: (M+H)+=641
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08420657B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-f0db11d801ec43779df29d2d7d130391 |
| Source note | uspto-grants-2013_04 |