HCID 68499992, compound → HCID 68499754, compound

HRID 1966496Notes

Reaction equation

HRID 1966496 reaction equation
[CH:1]1([O:6][C:7]([NH:9][C@@H:10]2[C:24](=[O:25])[N:23]3[CH2:26][C@H:27]([O:29][C:30]4[N:31]=[C:32]5[C:37](=[C:38]6[C:43]=4[CH:42]=[CH:41][CH:40]=[CH:39]6)[CH:36]=[C:35]([F:44])[CH:34]=[CH:33]5)[CH2:28][C@H:22]3[C:21](=[O:45])[NH:20][C@:19]3([C:47]([O:49]CC)=[O:48])[CH2:46][C@H:18]3[CH:17]=[CH:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]2)=[O:8])[CH2:5][CH2:4][CH2:3][CH2:2]1.C(OC(N[C@@H]1C(=O)N2C[C@H](OC3N=C4C(=C5C=3C=CC=C5)C=CC=C4)C[C@H]2C(=O)N[C@]2(C(OCC)=O)C[C@H]2C=CCCCCC1)=O)(C)(C)C>>[CH:1]1([O:6][C:7]([NH:9][C@@H:10]2[C:24](=[O:25])[N:23]3[CH2:26][C@H:27]([O:29][C:30]4[N:31]=[C:32]5[C:37](=[C:38]6[C:43]=4[CH:42]=[CH:41][CH:40]=[CH:39]6)[CH:36]=[C:35]([F:44])[CH:34]=[CH:33]5)[CH2:28][C@H:22]3[C:21](=[O:45])[NH:20][C@:19]3([C:47]([OH:49])=[O:48])[CH2:46][C@H:18]3[CH:17]=[CH:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]2)=[O:8])[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

3

Reactant 2

HCID 68499992HCID 68499992, compoundHCID 68500065HCID 68500065, compound

Product 1

HCID 68499754HCID 68499754, compound

Procedure

Example 37e was prepared according to the procedure used for the preparation of Example 67c, substituting the product of Example 37d for the product of Example 24b.

Workup

  1. customExample 37e was prepared
  2. customused for the preparation of Example 67c

Sources & evidence

ORD record
ord-22842ae6eda34900948e1b5641473090
Source dataset
uspto-grants-2013_04
Patent number
US08420596B2

Reaction notes

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