Pyridine-3-sulfonyl chloride → HCID 59474769, compound

HRID 1966521Notes

Reaction equation

HRID 1966521 reaction equation
Cl.Cl.[NH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:8]=[CH:9][CH:10]=[C:11]2[C:16]=1[N:15]=[C:14]([CH3:17])[CH:13]=[C:12]2[NH:18][CH2:19][C:20]1[CH:25]=[CH:24][C:23]([Cl:26])=[C:22]([Cl:27])[CH:21]=1.[N:28]1[CH:33]=[CH:32][CH:31]=[C:30]([S:34](Cl)(=[O:36])=[O:35])[CH:29]=1>>[Cl:27][C:22]1[CH:21]=[C:20]([CH:25]=[CH:24][C:23]=1[Cl:26])[CH2:19][NH:18][C:12]1[C:11]2[C:16](=[C:7]([O:6][CH2:5][CH2:4][NH:3][S:34]([C:30]3[CH:29]=[N:28][CH:33]=[CH:32][CH:31]=3)(=[O:36])=[O:35])[CH:8]=[CH:9][CH:10]=2)[N:15]=[C:14]([CH3:17])[CH:13]=1

Participants

3

Reactant 2

HCID 3164136Pyridine-3-sulfonyl chlorideHCID 25217580HCID 25217580, compound

Product 1

HCID 59474769HCID 59474769, compound

Procedure

Preparation was made using a similar procedure as described in example 21. Starting materials were [8-(2-aminoethoxy)-2-methylquinolin-4-yl]-(3,4-dichlorobenzyl)-amine dihydrochloride and pyridine-3-sulfonyl chloride.

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-a5a689ba55a2458d853c01901dc8aa18
Source dataset
uspto-grants-2013_04
Patent number
US08420670B2

Reaction notes

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