1-Propanesulfonyl chloride, 2-methyl- → HCID 25217586, compound

HRID 1966522Notes

Reaction equation

HRID 1966522 reaction equation
Cl.Cl.[NH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:8]=[CH:9][CH:10]=[C:11]2[C:16]=1[N:15]=[C:14]([CH3:17])[CH:13]=[C:12]2[NH:18][CH2:19][C:20]1[CH:25]=[CH:24][C:23]([Cl:26])=[C:22]([Cl:27])[CH:21]=1.[CH2:28]([S:32](Cl)(=[O:34])=[O:33])[CH:29]([CH3:31])[CH3:30]>>[Cl:27][C:22]1[CH:21]=[C:20]([CH:25]=[CH:24][C:23]=1[Cl:26])[CH2:19][NH:18][C:12]1[C:11]2[C:16](=[C:7]([O:6][CH2:5][CH2:4][NH:3][S:32]([CH2:28][CH:29]([CH3:31])[CH3:30])(=[O:34])=[O:33])[CH:8]=[CH:9][CH:10]=2)[N:15]=[C:14]([CH3:17])[CH:13]=1

Participants

3

Reactant 2

HCID 1822361-Propanesulfonyl chloride, 2-methyl-HCID 25217580HCID 25217580, compound

Product 1

HCID 25217586HCID 25217586, compound

Procedure

Preparation was made using a similar procedure as described in example 21. Starting materials were [8-(2-aminoethoxy)-2-methylquinolin-4-yl]-(3,4-dichlorobenzyl)-amine dihydrochloride and isobutanesulfonyl chloride.

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-73f5541768524db98702773b1234155c
Source dataset
uspto-grants-2013_04
Patent number
US08420670B2

Reaction notes

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