Methanesulfonyl chloride → HCID 59474803, compound

HRID 1966527Notes

Reaction equation

HRID 1966527 reaction equation
[NH2:1][CH2:2][CH2:3][O:4][C:5]1[CH:6]=[CH:7][CH:8]=[C:9]2[C:14]=1[N:13]=[C:12]([CH3:15])[CH:11]=[C:10]2[NH:16][CH2:17][C:18]1[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][C:19]=1[Cl:25].[CH3:26][S:27](Cl)(=[O:29])=[O:28]>>[Cl:25][C:19]1[CH:20]=[C:21]([Cl:24])[CH:22]=[CH:23][C:18]=1[CH2:17][NH:16][C:10]1[C:9]2[C:14](=[C:5]([O:4][CH2:3][CH2:2][NH:1][S:27]([CH3:26])(=[O:29])=[O:28])[CH:6]=[CH:7][CH:8]=2)[N:13]=[C:12]([CH3:15])[CH:11]=1

Participants

3

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 59474801[8-(2-Aminoethoxy)-2-methylquinolin-4-yl]-(2,4-dichlorobenzyl)-amine

Product 1

HCID 59474803HCID 59474803, compound

Procedure

Preparation was made using a similar procedure as described in example 21. Starting materials were [8-(2-aminoethoxy)-2-methylquinolin-4-yl]-(2,4-dichlorobenzyl)-amine (example 36) and methanesulfonyl chloride.

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-50f87fc5cc3d45d59c6142594f3a5df1
Source dataset
uspto-grants-2013_04
Patent number
US08420670B2

Reaction notes

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