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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1966536Generated: October 26, 2026

4-Chloro-8-methoxy-2-methylquinoline → [(R)-1-(4-Chlorophenyl)-ethyl]-(8-methoxy-2-methylquinolin-4-yl)-amine

https://huagongshe.com/reaction/1966536

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-8-methoxy-2-methylquinolineHCID 807583—
Reactant(1R)-1-(4-chlorophenyl)ethan-1-amineHCID 1715226—
Product[(R)-1-(4-Chlorophenyl)-ethyl]-(8-methoxy-2-methylquinolin-4-yl)-amineHCID 59474735—

Reaction Steps

Preparation was made using a similar procedure as described in example 41. Starting materials were 4-chloro-8-methoxy-2-methylquinoline and (R)-1-(4-chloro-phenyl)ethylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08420670B2
Source datasetuspto-grants-2013_04
ORD IDord-aeb8feb8a9254691bd826e287421f688
Source noteuspto-grants-2013_04